The frequency of sugar/refined carbohydrate intake may be the main dietary variable in caries etiology, affecting colonization with cariogenic bacteria and the development of caries. After bacteria metabolize sugar into acid, it takes 20 to 40 minutes for the acid to be neutralized or washed away by saliva. Therefore, the more frequently simple sugars and/or refined carbohydrates are consumed, the greater the potential period for demineralization. |