PROS Secondary Sexual Characteristics Study
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PROS Pearls:
* A 1997 PROS study on the emergence of puberty in young girls indicates
that signs of puberty are present in as many as 7% of white and 27%
of African American girls seen in practice by age 7 - earlier than
suggested in standard pediatric textbooks. This finding has led the
Lawson Wilkins Pediatric Endocrine Society to revise its recommendations
on the timing of referral for evaluation of precocious puberty in
girls.
* Practitioners may wish to begin to offer anticipatory guidance
regarding puberty to girls and their families at younger ages than
they have been accustomed to doing.
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The PROS Secondary Sexual Characteristics Study was funded by Genentech
Inc. The study was conducted between July 1992 and September 1993 in 65
PROS practices. Subjects included girls 3 through 12 years of age who
were being seen for a health supervision visit or for a problem that would
require a complete physical examination. Data from 17,077 girls were analyzed
in the study. The first study manuscript was published in the April 1997
issue of Pediatrics.
The citation and link to the manuscript follows below:
Herman-Giddens ME, Slora EJ, Wasserman RC, Bourdony CJ, Bhapkar MV, Koch
GG, Hasemeier CM. Secondary sexual characteristics and menses in young girls
seen in office practice: A study from the Pediatric Research in Office Settings
network. Pediatrics 1997; 99: 505-512.
| Core support for the
PROS network is provided by a grant from the Health Resources and
Services Administration Maternal and Child Health Bureau |
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Pediatric Research in Office Settings (PROS)
American Academy of Pediatrics
141 Northwest Point Blvd
PO Box 927
Elk Grove Village, IL 60009-0927
800/433-9016, ext. 7623
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