Pediatric Emergency Medicine

Collaborative Research Committee Meeting

May 3, 2004 - San Francisco

 

ATTENDEES
1	Kathleen Adelgais	10	Julie Brown	19	Maria Kwok	28	Kathy Shaw
2	Dewesh Agrawal	11	Brian Coleman	20	Nathan Kuppermann	29	Molly Stevens
3	Evie Alessandrini	12	Peter Dayan	21	Marlene Melzer-Lange	30	Donna Sutherland
4	Elizabeth Alpern	13	Amy Drendel	22	Russell Migita	31	Stephen Teach
5	Richard Bachur	14	Nanette Dudley	23	Rakesh Mistry	32	Jennifer Trainor
6	Lalit Bajaj	15	Marc Gorelick	24	Lise Nigrovic	33	Vincent Wang
7	Subhankar Bandyopadhyay	16	Halim Hennes	25	Mark Roback	34	Debra Weiner
8	Bema Bonsu	17	Michael Kim	26	Mary Rutherford	35	Ethan Wiener
9	David Brousseau	18	Eileen Klein	27	Angie Saulys	36	Kenneth Yen

 

 

I.          WELCOME AND SIGN-IN.  Several individuals were present for the first time and were welcomed to the group. 

 

II.         KEN GRAFF AWARD UPDATE.  Nate Kuppermann provided an update on the Ken Graff Young Investigator Award.  This year there were 23 first applications with the large majority were from fellows in training.  From these, 6 individuals have been invited to submit expanded proposals.  The Graff Award is currently being provided annually covered in part by the endowment and in part by funds provided from the section of emergency medicine of the AAP.  Current endowment is at approximately $120,000.00 and contributions continue to be solicited.  All those present were encouraged to contribute to the fund if possible.

 

III.        UPDATE ON EXISTING PROTOCOLS. 

            A.         High Dose Epinephrine Study - This study for which Mary Patterson is principal investigator, has finally been accepted for publication in Pediatric Emergency Care and will be appearing in the next few months. 

            B.         Pediatric Risk of Admission Score - Jim Chamberlain's PRISA validation study appeared in the April, 2004 Annals of Emergency Medicine.

            C.         Serious Bacterial Infection In Infants With RSV.  The results of this study will appear in Pediatrics in June, 2004.

            D.         Ongoing Studies -

                        1.         Inpatient vs. Outpatient Treatment of Infants With Urinary Tract Infection.  Peter Dayan of Columbia is leading this study.  Based on feedback from collaborators the study protocol has been revised and greatly simplified.  The complexity of the protocol was noted to be an important barrier to identifying interested centers and inpatient enrollment.  A revised protocol will be posted to the list serve.

                        2.         Analgesia for Children With Suspected Appendicitis.  Donna Sutherland and Charles Macias are leading this study.  They too identified protocol complexity as a barrier to progress and have simplified their proposal as well.  The main change is that repeat evaluation does not need to be performed by a surgeon.  Again, a revised protocol will be circulated via list serve.  Currently the study is ongoing at Texas Children's Hospital, Wake Medical Center in Raleigh, North Carolina and Emory in Atlanta.  Additional centers who may be interested were invited to contact the principal investigators. 

PEM Collaborative Research Meeting

San Francisco - May 3, 2004

Page 2

 

 

            E.         New Study Protocol.  A new protocol was endorsed by the review group this spring.  Dr. Lise Nigrovic from Boston Children's is the principal investigator.  The title of this study is "Multicenter Clinical Decision Rule for Identifying Children with Cerebrospinal Fluid Pleocytosis at Very Low Risk of Spinal Meningitis."  This study is intended to develop and validate a clinical prediction role to identify infants at very low risk of bacterial vs. viral meningitis.  The study is a retrospective cohort study.  The goal is to identify 10-15 interested centers.  A number of investigators have already contacted Dr. Nigrovic with interest after initial circulation of protocol.  Those who are interested in potentially participating or getting more information may contact her at lise.nigrovic@childrens.harvard.edu. 

 

The meeting was adjourned at 8:45 a.m. and all were encouraged to attend the PEM Specialty Interest Group Meeting at 9:00 a.m.  The next meeting will be in October, 2004 at the AAP National Conference and Exhibition in San Francisco.

 

 

Respectfully submitted: Marc Gorelick, MD

Transcribed: May13_04;pg

PEM Collaborative Meeting: May03_04