Spina bifida (SB) remains a major cause of lifelong disability worldwide. Although historically associated with high morbidity, outcomes have improved substantially due to:
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Primary prevention through folic acid fortification
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Early neurosurgical intervention, including fetal surgery
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Innovations in urologic reconstruction that address secondary complications
The information below synthesizes evidence demonstrating how these targeted interventions reduce SB incidence, enhance function, and improve quality of life. By integrating findings from population health, clinical trials, and surgical outcomes research, we illustrate how coordinated, evidence-based approaches reshape health trajectories for individuals with SB.
Acknowledgements
This project is supported by the Centers for Disease Control and Prevention of the U.S. Department of Health and Human Services (HHS) as part of a financial assistance award totaling $400,000 with 100 percent funded by CDC/HHS. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by CDC/HHS, or the U.S. Government.
Source
American Academy of Pediatrics