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Non-Operative Treatment For Appendicitis Deserves More Research: Study

Surgery has long been the mainstay of treatment for acute appendicitis, but a new review of research shows that antibiotics without surgical removal of the appendix may be an effective treatment for children and adults, according to an article in Pediatrics. The article, “Efficacy and Safety of Non-Operative Treatment for Acute Uncomplicated Appendicitis: A Meta Analysis,” will be published in the March 2017 issue of Pediatrics (published online Feb. 17). The authors reviewed existing literature published over the past 10 years that included 10 studies reporting on 413 children who received non-operative treatment rather than an appendectomy. No study reported any safety concern or specific adverse events related to non-surgical treatment, although the rate of recurrent appendicitis was 14 percent. The authors find a lack of robust evidence comparing non-operative treatment with surgery, but conclude that the data supports future research. The authors recommend that non-operative treatment for uncomplicated appendicitis be reserved for those participating in carefully designed research studies, preferably as large randomized trials.


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