Additional Resources


Additional Resources


Articles of Interest

As the approach to NAS care has evolved, diverse groups of providers have come together to actively assess and study evidence based practice and best outcomes for families and infants with NAS. The scholarly articles provided here are a small sampling of the long list of pivotal studies and public health data that have set the tone for improving care for the mother-infant dyad with OUD in pregnancy. Current foundations of NAS care include non-pharmacologic care, evaluation of pharmacologic care, standardized care practices and quality improvement, and emphasis on public health dimensions of comprehensive care for the mother-infant dyad.

Saiki T, et al. Neonatal abstinence syndrome – postnatal ward versus neonatal unit management. Eur J Pediatr (2010) 169:95-98

MacMillan KD, et al. Association of Rooming-in with outcomes for neonatal abstinence syndrome – A systematic review and meta-analysis. JAMA Pediatr. 2018

Maguire DJ. Care of the Infant with neonatal abstinence syndrome strength of the evidence. Journal of perinatal and neonatal nursing 2014

Brandt L, Finnegan LP. Neonatal abstinence syndrome: where are we, and where do we go from here? Curr Opin Psychiatry. 2017 Jul;30(4):268-274. Review.

Walsh MC, Crowley M, Wexelblatt S, et al. Ohio Perinatal Quality Collaborative Improves Care of Neonatal Narcotic Abstinence Syndrome. Pediatrics. 2018;141(4):e20170900

Grossman M, Berkwitt A. Neonatal Abstinence Syndrome. Semin Perinatol. 2019, Jan 15. pii: S0146-0005(19)30007-2. 

Wachman EM, Farrer LA. The genetics and epigenetics of Neonatal Abstinence Syndrome. Semin Fetal Neonatal Med. 2019, Apr 24, Epub 2019 Jan 25.

Favara MT, Carola D, Jensen E, Cook A, Genen L, Dysart K, Greenspan JS, Aghai ZH. Maternal breast milk feeding and length of treatment in infants with neonatal abstinence syndrome. J Perinatol. 2019 Apr 15.

Patrick SW, Bauer AM, Warren MD, Jones TF, Wester, C. Hepatitis C Virus Infection Among Women Giving Birth – Tennessee and United States, 2009-2014. MMWR, May 12, 2017, Vol 66, No 18. 

State Collaboratives

Many State Collaboratives exist that are dedicated to improving outcomes for mothers and infants with NAS.  A few are listed here. Access informative webinars, standardized care protocols and ideas, QI projects, and parent education materials. Many collaborative teams include our own AAP members! 

Ohio Perinatal Quality Collaborative

ILPQC (Illinois Perinatal Quality Collaborative) MNO Initiative (Mothers and Newborns Affected by Opioids) 

NeoQIC (Neonatal Quality Improvement Collaborative of Massachusetts)

State Perinatal Quality Collaboratives with NAS Programs