Academy of Pediatrics offers new guidance on diagnosing and managing serious
infections in infants born at less than 34 weeks gestation and those born at
more than 34 weeks of gestation in two clinical reports published in the
December 2018 issue of Pediatrics. The reports (published online Nov.
19) are titled, “Management of Neonates Born at ≥35 0/7 Weeks’ Gestation With Suspected or Proven Early-Onset Bacterial Sepsis” and “Management of Neonates Born at ≤34 6/7 Weeks’ Gestation With Suspected or Proven Early-Onset Bacterial Sepsis.” The AAP reports note that most preterm infants born with a very-low
birth weight are treated with antibiotics shortly after birth because of the
risk of early-onset sepsis, a serious, often fatal infection that begins in
utero or during labor. But research shows that antibiotic exposure after birth
also is associated with poor outcomes for some infants. The clinical reports
offer recommendations to physicians on how to identify babies most likely to
develop early-onset sepsis, based on their gestational age, circumstances of
birth and other factors, and addresses the use of multivariate sepsis risk
models in clinical care. The reports also examine the value of commonly used
laboratory tests and how to weigh the risks and benefits of administering
antibiotics to prevent early-onset sepsis.
The American Academy of Pediatrics is an organization of 67,000 primary care pediatricians, pediatric medical subspecialists and pediatric surgical specialists dedicated to the health, safety and well-being of infants, children, adolescents and young adults. For more information, visit www.aap.org and follow us on Twitter @AmerAcadPeds