DC – Chemicals called polybrominated diphenyl ethers (PBDEs) have been used
for decades to reduce fires in everyday products such as baby strollers,
carpeting and electronics. A new study to be presented on Monday, May 6, at the Pediatric Academic Societies
(PAS) annual meeting shows that prenatal exposure to the flame retardants is associated
with lower intelligence and hyperactivity in early childhood.
“In animal studies, PBDEs can
disrupt thyroid hormone and cause hyperactivity and learning problems,” said
lead author Aimin Chen, MD, PhD, assistant professor in the Department of
Environmental Health at University of Cincinnati College of Medicine. “Our
study adds to several other human studies to highlight the need to reduce
exposure to PBDEs in pregnant women.”
Chen and his colleagues collected blood samples from 309 pregnant women enrolled in a study at Cincinnati Children’s
Hospital Medical Center to measure PBDE levels. They also performed
intelligence and behavior tests on the women’s children annually until they
were 5 years old.
“We found maternal exposure to
PBDEs, a group of brominated flame retardants mostly withdrawn from the U.S.
market in 2004, was associated with deficits in child cognition at age 5 years
and hyperactivity at ages 2-5 years,” Dr. Chen said. A 10-fold increase in maternal
PBDEs was associated with about a 4 point IQ deficit in 5-year-old children.
Even though PBDEs, except Deca-BDEs, are not used as a flame
retardant in the United States anymore, they are found on many consumer products
bought several years ago. In addition, the
chemicals are not easily biodegradable, so they remain in human tissues and are
transferred to the developing fetus.
“Because PBDEs exist in the home and
office environment as they are contained in old furniture, carpet pads, foams and
electronics, the study raises further concern about their toxicity in developing
children,” Dr. Chen concluded.
view the abstract, “Cognitive Deficits and Behavior Problems in Children with
Prenatal PBDE Exposure,” go to http://www.abstracts2view.com/pas/view.php?nu=PAS13L1_3550.8.
The Pediatric Academic Societies (PAS)
are four individual pediatric organizations that co-sponsor the PAS Annual
Meeting – the American Pediatric Society, the Society for Pediatric Research,
the Academic Pediatric Association, and the American Academy of Pediatrics.
Members of these organizations are pediatricians and other health care
providers who are practicing in the research, academic and clinical arenas. The
four sponsoring organizations are leaders in the advancement of pediatric
research and child advocacy within pediatrics, and all share a common mission
of fostering the health and well-being of children worldwide. For more information, visit www.pas-meeting.org. Follow news of the PAS meeting on Twitter at http://twitter.com/PedAcadSoc.