STI Screening Guidelines

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​STI Screening Guidelines

​Although Sexually Transmitted Infections (STIs) affect individuals of all ages, STIs are particularly prevalent among young people. The Centers for Disease Control and Prevention (CDC) estimates that youth ages 15-24 make up just over one quarter of the sexually active population, but account for half of the 20 million new sexually transmitted infections that occur in the United States each year. The resources on this page provide information about the impact of STIs on youth as well as resources available for providing care to this population. Providers should address prevention, screening, and treatment of STIs with their sexually active adolescent and young adult patients as part of their regular annual health care visits. Below are some resources and tools on STIs to help providers prevent, manage, and treat these infections.

Types of Sexually Transmitted Infections

There are many types of sexually transmitted infections (STIs), but there are some that are more common in the adolescent and young adult population, which are listed below. For a full list of all STIs, please visit the CDC Web site

When screening for STIs, special considerations should be given for the following: 

  • HIV Screening: This screening should be done for EVERYONE ages 13-64. 

  • Screenings for Adolescents and Young Adults Under 25 Years of Age: Annual chlamydia and gonorrhea screenings should be done for women under age 25 as well as older women who are at risk. Screening for syphilis, HIV, chlamydia, and Hepatitis B should be given to all pregnant women, and gonorrhea screening for pregnant women at risk. 

  • Men Who Have Sex With Men (MSM): These men have higher rates of STIs, such as HIV and syphilis and should be tested for these as well as chlamydia and gonorrhea. 

  • Sex Workers: This population is at higher risk for HIV and other STIs than others, and should be tested at least annually for HIV. 

AAP Clinical Guidance For Providers 

Bright Futures Guidelines: These guidelines offer information, guidance, and tools for HIV screening. 

Periodicity Schedule: Provides recommended screenings for each age. 

Red Book: The authority on pediatric infectious diseases provides information on the epidemiology, evaluation, management, prevention, and treatment of HIV infection in adolescents.

Screening for non-viral STIs in Adolescents and Young Adults - Policy Statement 

Condom Use – Policy Statement 

Contraception for Adolescents – Policy Statement 

Contraception for Adolescents – Technical Report 

Policy Statements: The Committee on Pediatric Aids has several related policy statements on HIV. 

HPV Immunization Resources – This Web site has a variety of resources for providers on how to talk to families about HPV and how to improve immunization rates. 

CDC Resources

CDC STD Surveillance Data (2015) – Statistics and trends for STIs through 2015. 

Reported STDs in the US – A snapshot of the prevalence of STIs in the United States. 

National STD Curriculum: Launched in November 2017, this curriculum features self-study learning modules on a variety of STDs. 

Staying Healthy and Preventing STDs: This is a fact sheet for teens. 

STI and HIV Screening Recommendations: The CDC’s official STI/HIV screening recommendations. 

2015 CDC STD Treatment Guidelines: These are the current STD guidelines.
Download the 2015 STD Treatment (Tx) Guide app, an easy-to-use reference that combines information from the STD Treatment Guidelines as well as MMWR updates, and features a streamlined interface so providers can access treatment and diagnostic information. The free app is available for Apple devices and Android devices.

Gay, Bisexual, and Men Who Have Sex With Men (MSM): Specific screening and treatment guidelines are available for this population of men. 

CDC Screening Guidelines for Sex Workers: Information is available on the HIV/STI risk for this population as well as screening guidelines. 

Sexual Health Resource Exchange - A web-based resource library that provides access to high quality, accurate, multi-media public awareness and education materials on sexually transmitted infections and other sexual health issues. Users can search for, view and download customizable public awareness and educational materials. Users can also share their own resources using the easy-to-use upload process. The SHRE is managed by the National Coalition for Sexual Health. 

Sexual Risk Behaviors: HIV, STD, and Teen Pregnancy Prevention: These data report the prevalence of HIV, STDs, and teen pregnancy across the US. 

Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention: This resource provides information on interventions and best practices. 

Genital HSV Infections: There are 2 types of HSV infections and the CDC provides guidance on how to diagnose, treat, and prevent future infections. 

HPV Infection: The CDC offers information on HPV and the how to prevent this infection. The best way to prevent HPV is to get the vaccine in a series of 2 or 3 doses. The CDC recommends the vaccine is given to patients who are 11 or 12 years old.

Other Helpful Resources for Providers, Adolescents/Young Adults, and Parents 

Healthy Children: The AAP’s public-facing Web site provides information on STIs for adolescents, young adults, and parents, including: 

Physicians for Reproductive Health: Provides education on STI prevention, screening, and treatment for providers. 

Find an STI testing site.


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