Supply & Shortage
See below for general resources related to vaccine supply. In the case of disrupted supply, the following resources can keep you informed, and provide information to help keep your patients up to date.
Current Pediatric Vaccine Shortage
Pediatric hepatitis B vaccine Recombivax HB will not be available from Merck until April 2, 2018, according to the manufacturer. In a letter to providers, Merck said demand around the world and manufacturing process updates caused the shortage of Recombivax HB in both pediatric and adult formulations. This shortage impacts the following package sizes: ten (10) 5 mcg/0.5 mL single-dose pre-filled Luer-Lok® syringes with tip caps and 5mcg/0.5mL - 10 single-dose 0.5mL vials. More information can be found on the Merck Supply Status page.
There is no change in the recommendations for hepatitis B vaccine administration – 3 dose series (birth, 1-2 months of age and 6-18 months of age). For more information about hepatitis B and current hepatitis B vaccination recommendations, see the AAP Vaccine Preventable Diseases and Policy page.
GlaxoSmithKline (GSK) has an adequate supply of Engerix-B hepatitis B vaccine to make up for the shortage, but it only will be available in prefilled syringes. The two monovalent vaccines are interchangeable. For more information regarding ordering supply from GSK, visit the GSK Direct Website or reference the GSK Direct Customer Resource Guide.
AAP announces the hepatitis B shortage to members via AAP News, Merck HepB vaccine unavailable until April; GSK has supply.