Pediatric Research in Office Settings (PROS), founded in 1986, is the practice-based research network of the AAP. Its mission is to improve the health of children and enhance primary care practice by conducting and fostering national collaborative practice-based research.​

Primary Care Research Network

About PROS

  • Practice-based research network of the AAP
  • Established in 1986
  • > 400 unique practices have participated in at least 1 study since 2010
  • Based at AAP headquarters in the Chicago area
  • Collaborates with researchers around the country

Our Mission

To improve the health of children and enhance primary care practice by conducting and fostering national collaborative practice-based research.

Guiding Principles

  • Pediatric practice is the appropriate laboratory for studying primary care issues
  • The wisdom of our member pediatricians is wed to scientifically sound research methods
  • Collaborate with other research groups
  • Serve as a resource to other research networks
  • Disseminate results to influence clinical policies and improve care
  • Contribute to the evidence base and study the best ways to implement that evidence
  • Ensure our projects are consistent with the mission of the AAP and further its goals and objectives

Our Core Values

  • PROS is dedicated to:
    • Defining and advancing the best care for all children
    • Performing research that is meaningful to pediatricians
    • Creating a community of caring researchers and pediatricians
    • Fostering ongoing research relationships and camaraderie to advance child health research and invigorate pediatricians
    • Cultivating relationships within the broader child health research community
  • PROS values the unique contributions of every member and participant
  • PROS studies emphasize and strive for: elegance, simplicity and practicality ​

CER2 Consortium

The Comparative Effectiveness Research through Collaborative Electronic Reporting ​(CER2) consortium:

Capable of supporting research on a wide range of topics.

Dataset inludes:
> 2 million children
7 organizations
222 practice sites
27 states

Clinical Studies

PROS studies advance the knowledge on which pediatric primary care is based. This list comprises our active study topics.

A study to identify strategies for using telemedicine in primary care in ways that improve child health and health equity.

Reducing adolescent drinking
Adolescent Substance use Prevention Intervention Research study

COVID-19, Influenza vaccines, and Text Messages
The goal of the study is to better understand the effectiveness and implementation of COVID-19 vaccine and influenza (flu) vaccine text message reminders . 

Suicide prevention  
A study to collect preliminary feasibility and effectiveness data on a digital suicide prevention intervention. 

Last Updated



American Academy of Pediatrics